ea0031oc3.6 | Reproduction, growth and development | SFEBES2013
Robertson Rachel
, Mahmood Waheed
, McGonnell Imelda
, Mukherjee Abir
Follistatin-like 3 (FSTL3) is an endogenous glycoprotein inhibitor of transforming growth factor-β (TGFβ) ligands such as activin. TGFβ ligands are integral to key cellular processes such as proliferation, development and differentiation, including angiogenesis. It is not clear, however, how FSTL3 and activin action affect tissue and organ functions in health and disease. We have identified a group of activin-responsive genes that have an expression pattern clos...